In an intriguing turn of events, a growing number of male users of Ozempic—a medication primarily prescribed for weight loss—are reporting unexpected and surprising side effects. Many claim that since starting this injection, they have noticed a significant increase in the size of their penises, leading to a flurry of discussions on various online forums.

Ozempic, which was made widely available across the United States in 2024, has been hailed as a miracle drug for those struggling with obesity. Its active ingredient, semaglutide, works by mimicking a hormone that targets areas of the brain involved in regulating appetite and food intake. However, beyond its weight loss capabilities, some men have found themselves celebrating what they are referring to as “Ozempic penis” or “Ozemd**k.”

In a recent Reddit thread, an anonymous user shared, “I recently measured myself down there and noticed I gained about one inch.” This comment sparked a wave of responses from other users who echoed similar experiences. One enthusiastic Redditor exclaimed, “I gained 1.5 inches in length. No joke. Like you, I obviously know how long I was before I got very fat. After about seven months on Tirzepatide, I gained 1.5 inches. Definitely not all from weight loss.”

Many participants in the conversation noted that while they attributed their perceived increase in size to weight loss, they also recognized other contributing factors. One commenter mentioned, “Yeah, my wife has definitely noticed a difference; I was 278 lbs, now I’m under 200 lbs.” This suggests that the combination of losing weight and improved blood circulation might also play a role in these reported changes.

However, not everyone is convinced that Ozempic is directly responsible for these claims. A skeptical Redditor pointed out, “I feel like nobody is really reading what you are writing; they blame the weight loss while you measured the first time when you were actually lighter.” This response highlights the importance of context when measuring such changes.

Experts caution that while weight loss can lead to a more pronounced appearance of genital size due to reduced fat in the pubic area, the notion that Ozempic directly increases penis size is likely a misconception. Factors such as time of day, temperature, and overall health can significantly affect the measurements of an erect penis. As one expert put it, “Ozempic does not enlarge your penis, but an erect penis may change size considerably depending on various external conditions.”

This phenomenon joins a list of other unusual side effects associated with Ozempic use. Another condition, referred to as “Ozempic mouth,” has caught users' attention, characterized by noticeable folds at the corners of the mouth, increased wrinkles on the lips, and sagging skin along the lip contours and chin area. Alarmed by these changes, some users have turned to cosmetic treatments like dermal fillers to restore lost volume in their facial areas.

The discussions surrounding these side effects underscore the complexity of medications like Ozempic and the need for users to remain informed about both intended and unintended outcomes. As the conversation continues to unfold in online communities, many will be watching closely to see how these narratives develop and what they might reveal about the multifaceted effects of weight-loss medications.